His wife, Monique, announced Brown's death in an Instagram post Friday afternoon. She said Brown "passed peacefully" Thursday night in their home in Los Angeles.
"To the world he was an activist, actor, and football star," the post read. "To our family he was a loving and wonderful husband, father, and grandfather. Our hearts are broken..."
In 2020, Brown was selected to the NFL 100 all-time team and also was ranked as the No. 1 all-time player on the College Football 150 list to celebrate those sports' anniversaries. He was named the greatest football player ever by the Sporting News in 2002.
Brown, who was selected in the first round of the 1957 draft, played nine seasons for the Cleveland Browns (1957-65) and led the league in rushing eight of those years. He rushed for 12,312 yards and held a 5.2 yards per carry average over his career. He also was named a Pro Bowler every year he played. He led the Browns to the league championship game three times, winning the title in 1964, and was named MVP three times.
He ran for at least 100 yards in 58 of his 118 regular-season games, never missing a game. He rushed for more than 1,000 yards in seven seasons, including 1,527 yards in one 12-game season and 1,863 in a 14-game season.
"It's impossible to describe the profound love and and gratitude we feel for having the opportunity to be a small piece of Jim's incredible life and legacy," the Browns said in a statement. "We mourn his passing, but celebrate the indelible light he brought to the world.
"Our hearts are with Jim's family, loved ones, and all those he impacted along the way."
Brown retired at 30, at the top of his career. He was filming the movie "The Dirty Dozen" during the offseason in 1966, and production went long because of bad weather. Browns owner Art Modell threatened to suspend Brown's pay if he didn't report to training camp on time. Brown opted to retire, saying he wanted to focus on his movie career and social issues.
Since his retirement, no Browns player has worn his No. 32 and a statue of him went up outside of FirstEnergy Stadium in 2016.